The effectiveness of mineralized plasmatic matrix in the closure of alveolar clefts with volumetric assessment
| Autor: | Gotike Siva Prasad Reddy, Padminii Ellapakurthi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
PRP Alveolar cleft defects medicine.medical_treatment Radiography Fistula Matrix (biology) volumetric assessment 03 medical and health sciences 0302 clinical medicine Iliac bone Medicine 030212 general & internal medicine Reduction (orthopedic surgery) business.industry SABG 030206 dentistry General Medicine respiratory system medicine.disease Oro-Nasal Fistula Platelet-rich fibrin Surgery Platelet-rich plasma Original Article Alveolar bone grafting business PRF |
| Zdroj: | Regenerative Medicine Research Regenerative Medicine Research, Vol 9, p 1 (2021) |
| ISSN: | 2050-490X |
| Popis: | Objectives: The purpose of this study is to assess the effectiveness of mineralized plasmatic matrix in the soft tissue closure of naso-alveolar fistula, to estimate the postoperative bone fill and volume of the graft placed in the alveolar cleft defect using cone-beam computed tomography (CBCT) at 3rd- month and 6th- month. Material and methods: 10 patients, in the age group of 15‑30 years were included in this study. They were diagnosed with unilateral cleft lip and alveolus defects with or without a cleft palate requiring late secondary alveolar bone grafting. Alveolar cleft defects were closed with mineralized plasmatic matrix (MPM), a combination of autogenous iliac bone graft and platelet rich plasma (PRP) and platelet rich fibrin (PRF). Results: The mean defect volume pre-operatively is 0.75 cm3 and at the end of 3rd-month postoperatively is 0.51 cm3 and at 6th-month postoperatively is 0.27 cm3. The average percentage of bone fill between preoperative (A) & 3th- month postoperatively (B) is 33.4% and between 3rd-month (B) and 6th-month post operatively (C) is 49.5%. Conclusions: Utilization of this new matrix (MPM), has shown to be effective in the closure of the cleft defect, oro-nasal fistula and also reduction in the volume of the residual cleft defect seen with sequential cone-beam computed tomography (CBCT) radiographs. |
| Databáze: | OpenAIRE |
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