Urinary tract anomalies and urinary tract dysfunction in children with Hirschsprung disease—Is follow-up indicated?
| Autor: | Anna Börjesson, Pernilla Stenström, Einar Arnbjörnsson, Hedda Marschall Sima, Kristine Hagelsteen, Christina Granéli |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Urologic Diseases Pediatrics medicine.medical_specialty Constipation Urinary system medicine.medical_treatment Urination Disease 03 medical and health sciences 0302 clinical medicine Enuresis 030225 pediatrics Prevalence medicine Humans Abnormalities Multiple Hirschsprung Disease Child Urinary Tract Renal agenesis Hydronephrosis Digestive System Surgical Procedures Ultrasonography Sweden business.industry General Medicine medicine.disease Nephrectomy Cross-Sectional Studies medicine.anatomical_structure Child Preschool 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health Urologic Surgical Procedures Female Surgery medicine.symptom business Renal pelvis Follow-Up Studies |
| Zdroj: | Journal of Pediatric Surgery. 54:2012-2016 |
| ISSN: | 0022-3468 |
| Popis: | Background/Purpose Urinary tract function in children with Hirschsprung disease (HD) is rarely considered. Aim: to evaluate the prevalence of urinary tract anomalies and dysfunction in children with HD compared to controls. Methods This was an observational cross sectional case–control study. Children with HD who underwent transanal endorectal pull-through technique (TERPT) from 2005 to 2017 were invited to participate. Ultrasound of the urinary tract was performed postoperatively. Children > 4 years were asked to answer a urinary tract function questionnaire. Controls were age-matched healthy children. Ethical approval was obtained. Results Seventy two children with HD and TERPT were included. Ultrasound was performed in 58 children (83%) post-TERPT. Ten anomalies were diagnosed in six children (10%). Structural anomalies included abnormal kidney size (7%), renal agenesis (2%), prominent calyces (2%) and renal pelvis anomaly (25). Probable acquired anomalies included hydronephrosis (2%), hydroureter (2%) and parenchymal damage (2%). One child had a prior nephrectomy owing to a Wilms' tumor. All 37 children > 4 years (27 boys and 10 girls), median aged 8 years (range 4–12), answered the questionnaire as did 284 healthy controls (144 boys and 140 girls). Boys with HD reported a higher frequency of enuresis: 65% versus 9% (p = 0.001) and urinary tract infections: 18% versus 3% (p = 0.012). Girls with HD reported enuresis more frequently (60%) than healthy girls (7%) (p = 0.001). Children with HD with constipation reported enuresis more frequently (p = 0.038). Conclusions Urinary tract anomalies and dysfunction deserve attention in the follow-up of children with HD. We suggest screening for urinary tract anomalies and urinary tract symptoms in follow-up of children with HD. Type of study Treatment study. Level III. |
| Databáze: | OpenAIRE |
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