Focusing of Microcrystals and Liquid Condensates in Acoustofluidics
| Autor: | Joris Van Lindt, Marzena Krzek, Wim De Malsche, Sander Stroobants, Anna Bratek-Skicki, Iwona Ziemecka, Pierre Philippe Gelin, Peter Tompa, Dominique Maes |
|---|---|
| Přispěvatelé: | Chemical Engineering and Industrial Chemistry, Faculty of Engineering, Faculty of Sciences and Bioengineering Sciences, Department of Bio-engineering Sciences, Structural Biology Brussels, Centre for Molecular Separation Science & Technology, Chemical Engineering and Separation Science |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
focusing General Chemical Engineering Microfluidics microfluidics acoustic radiation Nanotechnology 02 engineering and technology free electron laser crystal harvesting microcrystals law.invention particle separation Inorganic Chemistry 03 medical and health sciences Particle separation law lcsh:QD901-999 General Materials Science serial crystallography Jet (fluid) Free-electron laser Acoustic wave Injector liquid-liquid phase separation 021001 nanoscience & nanotechnology Condensed Matter Physics 3. Good health 030104 developmental biology Particle lcsh:Crystallography 0210 nano-technology |
| Zdroj: | Crystals Volume 9 Issue 3 Crystals, Vol 9, Iss 3, p 120 (2019) |
| Popis: | Manipulation of high-density materials, such as crystals and liquid condensates, is of great importance for many applications, including serial crystallography, structural and molecular biology, chemistry, and medicine. In this work, we describe an acoustic technique to focus and harvest flowing crystals and liquid condensates. Moreover, we show, based on numerical simulations, that the acoustic waves can be used for size-based particle (crystals, droplets, etc.) separation. This is an essential technological step in biological research, medical applications, and industrial processes. The presented technology offers high precision, biocompatibility, ease of use and additionally, is non-invasive and inexpensive. With the recent advent of X-ray Free Electron Laser (XFEL) technology and the associated enormous importance of a thin jet of crystals, this technology might pave the way to a novel type of XFEL injector. |
| Databáze: | OpenAIRE |
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