Fish oil decreases natural resistance of mice to infection with Salmonella typhimurium
| Autor: | I. Vladoianu, Lucien Girardier, P.F. Piguet, Hernan R. Chang, Denis Arsenijevic, Jean-Claude Pechère, Abdul G. Dulloo |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Salmonella typhimurium
medicine.medical_specialty Salmonella Ratón Diet therapy Endocrinology Diabetes and Metabolism medicine.disease_cause Microbiology Mice Fish Oils Endocrinology Animal science Internal medicine medicine Animals Salmonella Infections Animal biology Body Weight biology.organism_classification Fish oil Dietary Fats Enterobacteriaceae Immunity Innate Natural resistance Adipose Tissue Female Corn oil Bacteria |
| Zdroj: | Metabolism. 41:1-2 |
| ISSN: | 0026-0495 |
| DOI: | 10.1016/0026-0495(92)90181-9 |
| Popis: | Mortality rate in mice fed fish oil for 4 weeks was remarkably higher after a very low peroral (PO) challenge with Salmonella typhimurium, as compared with those fed diets rich in either corn oil or hydrogenated coconut oil, or a low fat (chow) diet. None of the surviving mice fed the fish oil diet showed bacterial counts in their spleens, unlike 45.4% to 66.6% of surviving mice fed high fat or low fat diets. The spleens of mice fed fish oil presented the highest number of bacteria 7 days after intraperitoneal infection with the same bacterial strain. Thus, the current studies demonstrate that a diet rich in fish oil decreases host resistance to infection. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|