Invasive group A streptococcal infections in adults, France (2006–2010)

Autor: Plainvert, C., Doloy, A., Loubinoux, J., Lepoutre, A., Collobert, G., Touak, G., Bouvet, A., Trieu-Cuot, P., Poyart, C., Network, C. Nr-Strep
Přispěvatelé: Institut Cochin (IC UM3 (UMR 8104 / U1016)), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre national de Référence des Streptocoques (CNR), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Département des maladies infectieuses, Institut de Veille Sanitaire (INVS), Biologie des Bactéries Pathogènes à Gram-positif, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP), This study was partly funded by the Institut National de Veille Sanitaire (INVS), the Assistance Publique-Hôpitaux de Paris (AP-HP), INSERM, and by a grant from ANR in the frame of ERA-Net PathoGenoMics., ANR-06-PATH-0012,Systematic analyses of kinase and phosphatase function in morphological, environmental, and virulence responses of the human fungal pathogen Candida albicans,Systematic analyses of kinase and phosphatase function in morphological, environmental, and virulence responses of the human fungal pathogen Candida albicans(2006), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), Institut Cochin ( UM3 (UMR 8104 / U1016) ), Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ), Assistance publique - Hôpitaux de Paris (AP-HP), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique ( CNRS ), ANR-06-PATH-0012,Systematic analyses of kinase and phosphatase function in morphological, environmental, and virulence responses of the human fungal pathogen Candida albicans,Systematic analyses of kinase and phosphatase function in morphological, environmental, and virulence responses of the human fungal pathogen Candida albicans ( 2006 )
Rok vydání: 2012
Předmět:
Male
Antibiotic resistance
Antibiotics
Bacteremia
[ SDV.MP.BAC ] Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology
medicine.disease_cause
Epidemiology
Case fatality rate
Prevalence
Fasciitis
Aged
80 and over

0303 health sciences
Pleuropneumonia
General Medicine
Middle Aged
Shock
Septic

Anti-Bacterial Agents
3. Good health
Infectious Diseases
emm type
invasive infections
Female
epidemiology
France
Adult
Microbiology (medical)
medicine.medical_specialty
Adolescent
Streptococcus pyogenes
medicine.drug_class
Microbial Sensitivity Tests
Biology
Microbiology
Young Adult
03 medical and health sciences
Streptococcal Infections
Drug Resistance
Bacterial

medicine
Humans
Fasciitis
Necrotizing

Aged
030304 developmental biology
030306 microbiology
group A streptococcus
medicine.disease
[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology
Molecular Typing
Streptococcus agalactiae
Zdroj: Clinical Microbiology and Infection
Clinical Microbiology and Infection, 2012, 18 (7), pp.702-710. ⟨10.1111/j.1469-0691.2011.03624.x⟩
Clinical Microbiology and Infection, Elsevier for the European Society of Clinical Microbiology and Infectious Diseases, 2012, 18 (7), pp.702-710. ⟨10.1111/j.1469-0691.2011.03624.x⟩
Clinical Microbiology and Infection, Elsevier for the European Society of Clinical Microbiology and Infectious Diseases, 2012, 18 (7), pp.702-710. 〈10.1111/j.1469-0691.2011.03624.x〉
ISSN: 1198-743X
1469-0691
Popis: International audience; Severe invasive group A streptococcal diseases have re-emerged during the past 10-20 years. In order to provide a better insight into the current epidemiological situation in France, we analysed the questionnaires regarding all invasive strains received at the National Reference Center for Streptococci (CNR-Strep) between 2006 and 2010 from patients aged ≥18 and characterized them by emm typing, spe gene detection and antibiotic resistance. Among the 1542 invasive GAS strains studied, 78% (n = 1206) were from blood cultures, and a streptococcal toxic shock syndrome (STSS) was described in 22% (n = 340) of cases, mainly associated with necrotizing fasciitis (NF) and pleuro-pulmonary infections (p
Databáze: OpenAIRE