European ST80 community-associated methicillin-resistant Staphylococcus aureus orbital cellulitis in a neonate
| Autor: | George A. Syrogiannopoulos, Marianna Vlychou, Aspasia N. Michoula, Fani Zacharaki, Evangelia E. Tsironi, Efthimia Petinaki, Sophia V. Tachmitzi, Ioanna N. Grivea |
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| Jazyk: | angličtina |
| Předmět: |
Male
Methicillin-Resistant Staphylococcus aureus Staphylococcus aureus medicine.medical_specialty Treatment outcome Case Report medicine.disease_cause Community associated Pharmacotherapy Daptomycin lcsh:Ophthalmology Internal medicine medicine Humans Intensive care medicine Greece business.industry Infant Newborn General Medicine Orbital Cellulitis biochemical phenomena metabolism and nutrition medicine.disease Methicillin-resistant bacterial infections and mycoses Methicillin-resistant Staphylococcus aureus Neonatal orbital cellulitis Anti-Bacterial Agents Community-Acquired Infections Ophthalmology Treatment Outcome lcsh:RE1-994 Drug Therapy Combination Orbital cellulitis business medicine.drug |
| Zdroj: | BMC Ophthalmology, Vol 12, Iss 1, p 7 (2012) BMC Ophthalmology |
| ISSN: | 1471-2415 |
| DOI: | 10.1186/1471-2415-12-7 |
| Popis: | Background Methicillin-resistant Staphylococcus aureus is a serious cause of morbidity and mortality in hospital environment, but also, lately, in the community. This case report is, to our knowledge, the first detailed description of a community-associated methicillin-resistant S. aureus ST80 orbital cellulitis in a previously healthy neonate. Possible predisposing factors of microbial acquisition and treatment selection are also discussed. Case presentation A 28-day-old Caucasian boy was referred to our hospital with the diagnosis of right orbital cellulitis. His symptoms included right eye proptosis, periocular edema and redness. Empirical therapy of intravenous daptomycin, rifampin and ceftriaxone was initiated. The culture of pus yielded a methicillin-resistant S. aureus isolate and the molecular analysis revealed that it was a Panton-Valentine leukocidine-positive ST80 strain. The combination antimicrobial therapy was continued for 42 days and the infection was successfully controlled. Conclusions Clinicians should be aware that young infants, even without any predisposing condition, are susceptible to orbital cellulitis caused by community-associated methicillin-resistant S. aureus. Prompt initiation of the appropriate empirical therapy, according to the local epidemiology, should successfully address the infection, preventing ocular and systemic complications. |
| Databáze: | OpenAIRE |
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