Pathogenicity mechanisms and host response during oral Candida albicans infections
| Autor: | Julian R. Naglik, Betty Hebecker, Ilse D. Jacobsen, Bernhard Hube |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Microbiology (medical)
Innate immune system Host (biology) medicine.medical_treatment Defence mechanisms Biofilm Immunosuppression Biology biology.organism_classification medicine.disease_cause Microbiology Oropharyngeal Candidiasis Infectious Diseases Candidiasis Oral Risk Factors Staphylococcus aureus Virology Candida albicans Host-Pathogen Interactions Immunology medicine Humans Immunity Mucosal |
| Zdroj: | Expert Review of Anti-infective Therapy. 12:867-879 |
| ISSN: | 1744-8336 1478-7210 |
| Popis: | Oral candidiasis remains one of the most common forms of Candida infections and occurs if the balance between host, Candida and microbiota is disturbed, e.g., by broad spectrum antibiotics or immunosuppression. In recent years, identification of fungal factors contributing to host cell damage and new insights into host defense mechanisms have significantly extended our understanding of the pathogenesis of oral candidiasis. In this review, we will provide an overview of the pathogenicity mechanisms during oral Candida infections and discuss some approaches by which this knowledge could be transferred into therapeutic approaches. |
| Databáze: | OpenAIRE |
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