| Popis: |
Background & objectives: Anaemia is a major health problem worldwide, as it affects nearly 500 million women and more than 1 billion women are at risk. Anaemia also leads to defects in neurotransmitter development and myelination which can slow down the conduction rate in neurons. This study was aimed to assess Sensory nerve conduction of median nerve in upper limb and Sural nerve in lower limb, to compare the sensory nerve conduction velocity (NCV) and amplitude between anaemic and non anaemic women and to correlate nerve conduction velocity and haemoglobin concentration. Methods: This was a cross sectional study. Individuals who met the inclusion criteria were recruited into the study. The subjects were screened for Complete Blood Count (CBC) Parameters and were selected accordingly. The Haemoglobin concentration was estimated using auto analyser by Spectrophotometry method. For this 2 mL of venous blood was withdrawn from the volunteers following aseptic precautions. The number of volunteers screened were 45. The numbers of volunteers recruited into study group were 33. Nerve conduction studies for the study and control subjects were conducted at the Electrophysiology lab, Department of Physiology. Sensory nerve conduction of the median nerve in upper limb and sural nerve in Lower limb were studied. Interpretation and Results: Subjects in the study and control groups were age, height and weight matched. Sensory nerve conduction velocity of median nerve was significantly reduced and the latency was prolonged in study group when compared to the control group. In sural nerve, the conduction velocity was reduced in the study group. Conclusion: We conclude from our study that, due to decreased myelination and decreased rate and amount of neurotransmitter synthesis, The Nerve conduction Velocity of peripheral nerves decrease and their latencies increase in Anaemic women when compared to Non-Anaemic women. |
