Multi-color magnetic particle imaging for cardiovascular interventions
| Autor: | Florian M. Vogt, Julian Haegele, Jörn Borgert, Jürgen Rahmer, Jörg Barkhausen, Sarah Vaalma, N Panagiotopoulos |
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| Rok vydání: | 2016 |
| Předmět: |
Diagnostic Imaging
Materials science Volume of interest Superparamagnetic iron oxide nanoparticles Color Image processing Nanotechnology 02 engineering and technology Iterative reconstruction Imaging phantom 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Magnetic particle imaging Imaging Three-Dimensional Medical imaging Image Processing Computer-Assisted Humans Radiology Nuclear Medicine and imaging Magnetite Nanoparticles Radiological and Ultrasound Technology Phantoms Imaging Models Cardiovascular 021001 nanoscience & nanotechnology 0210 nano-technology Lumen (unit) Biomedical engineering |
| Zdroj: | Physics in medicine and biology. 61(16) |
| ISSN: | 1361-6560 |
| Popis: | Magnetic particle imaging (MPI) uses magnetic fields to visualize the spatial distribution of superparamagnetic iron oxide nanoparticles (SPIOs). Guidance of cardiovascular interventions is seen as one possible application of MPI. To safely guide interventions, the vessel lumen as well as all required interventional devices have to be visualized and be discernible from each other. Until now, different tracer concentrations were used for discerning devices from blood in MPI, because only one type of SPIO could be imaged at a time. Recently, it was shown for 3D MPI that it is possible to separate different signal sources in one volume of interest, i.e. to visualize and discern different SPIOs or different binding states of the same SPIO. The approach was termed multi-color MPI. In this work, the use of multi-color MPI for differentiation of a SPIO coated guide wire (Terumo Radifocus 0.035″) from the lumen of a vessel phantom filled with diluted Resovist is demonstrated. This is achieved by recording dedicated system functions of the coating material containing solid Resovist and of liquid Resovist, which allows separation of their respective signal in the image reconstruction process. Assigning a color to the different signal sources results in a differentiation of guide wire and vessel phantom lumen into colored images. |
| Databáze: | OpenAIRE |
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