Does conduit artery diameter vary according to the anthropometric characteristics of children or men?
| Autor: | Keith George, Nicola McWhannell, Daniel J. Green, Gareth Stratton, Nigel Timothy Cable, Toni M. Tinken, Dick H. J. Thijssen, Laura Sutton, Nicola D. Hopkins |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Aging medicine.medical_specialty Health aging / healthy living [IGMD 5] Adolescent Brachial Artery Physiology Empirical Research Young Adult Absorptiometry Photon Electrical conduit Physiology (medical) Internal medicine medicine Humans Least-Squares Analysis Child Dual-energy X-ray absorptiometry Cardiovascular diseases [NCEBP 14] medicine.diagnostic_test business.industry Body Weight Age Factors Models Cardiovascular Ultrasonography Doppler Middle Aged Anthropometry Body Height Surgery medicine.anatomical_structure Body Composition Linear Models Cardiology Female Cardiology and Cardiovascular Medicine business Artery |
| Zdroj: | American Journal of Physiology : Heart and Circulatory Physiology, 297, 6, pp. H2182-7 American Journal of Physiology : Heart and Circulatory Physiology, 297, H2182-7 |
| ISSN: | 1522-1539 0363-6135 |
| DOI: | 10.1152/ajpheart.00228.2009 |
| Popis: | Arterial measurements are commonly undertaken to assess acute and chronic adaptations to exercise. Despite the widespread adoption of scaling practices in cardiac research, the relevance of scaling for body size and/or composition has not been addressed for arterial measures. We therefore investigated the relationships between brachial artery diameter and body composition in 129 children aged 9 to 10 yr (75 girls and 54 boys), and 50 men aged 16–49 yr. Body composition variables (total, lean, and fat mass in the whole body, arm, and forearm) were assessed by dual-energy X-ray absorptiometry, and brachial artery diameter was measured using high-resolution ultrasound. Bivariate correlations were performed, and arterial diameter was then scaled using simple ratios ( y/ x) and allometric approaches after log-log least squares linear regression and production of allometric exponents ( b) and construction of power function ratios ( y/ x b). Size independence was checked via bivariate correlations ( x: y/ x; x: y/ x b). As a result, significant correlations existed between brachial artery diameter and measures of body mass and lean mass in both cohorts ( r = 0.21–0.48, P < 0.05). There were no significant relationships between diameter and fat mass. All b exponents were significantly different from 1 (0.08–0.50), suggesting that simple ratio scaling approaches were likely to be flawed. This was confirmed when ratio scaling produced negative residual size correlations, whereas allometric scaling produced size-independent indexes ( r = 0.00 to 0.03, P > 0.05). In conclusion, when between- or within-group comparisons are performed under circumstances where it is important to control for differences in body size or composition, allometric scaling of artery diameter should be adopted rather than ratio scaling. Our data also suggest that scaling for lean or total mass may be more appropriate than scaling for indexes of fat mass. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|