Circulation in the Breast after Radiotherapy and Breast Conservation
| Autor: | B. Boné, Leif Svensson, Rimma Danielsson, Fuat Celebioglu, L. Perbeck, Marie Aastrup |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Mammary gland Breast Neoplasms Mastectomy Segmental Quadrant (abdomen) Breast cancer Carcinoma Humans Medicine Breast Postoperative Period Skin integumentary system business.industry Lumpectomy Radiotherapy Dosage Middle Aged medicine.disease Surgery Radiation therapy medicine.anatomical_structure Circulation (fluid dynamics) Regional Blood Flow Skin circulation Female Radiotherapy Adjuvant business |
| Zdroj: | The European Journal of Surgery. 167:497-500 |
| ISSN: | 1102-4151 |
| DOI: | 10.1080/110241501316914858 |
| Popis: | To investigate the breast circulation after radiotherapy and breast conservation.Open clinical study.University hospital, Sweden.24 patients with breast cancer (mean age 54 years, range 41-64).The glandular and the subcutaneous circulation in the breast were measured by Xenon (133Xe) clearance and the skin circulation by laser Doppler fluxmetry (LDF) two to five years after radiotherapy (50 Gy) following lumpectomy. The subcutaneous circulation was measured 2 cm above and medial or lateral to the areolar border and the glandular circulation 2 cm below and medial or lateral to the areolar border in the quadrant not previously operated on for carcinoma. The skin circulation was measured at the corresponding sites.Circulation in the subcutaneous and glandular tissue measured by 133Xe clearance and in the skin by LDF.The subcutaneous circulation, expressed as the ratio of 133Xe clearance in the operated irradiated: non-operated non-irradiated breast, was 0.88 (0.94) (median, interquartile range) and the glandular circulation 0.93 (0.75). The skin circulation ratios over the corresponding areas were 1.00 (0.37) and 1.00 (0.38), respectively.Radiotherapy after breast conservation surgery does not lead to long-term changes in basal glandular, subcutaneous, or skin circulation in the breast. |
| Databáze: | OpenAIRE |
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