The chorioallantoic membrane: A novel approach to extrapolate data from a well-established method
| Autor: | Alessandro Maugeri, Giovanni E. Lombardo, Michele Navarra, Santa Cirmi, Antonio Rapisarda |
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| Rok vydání: | 2021 |
| Předmět: |
Vascular Endothelial Growth Factor A
chorioallantoic membrane (CAM) Neovascularization Pathologic Neovascularization Physiologic Reproducibility of Results Chick Embryo toxicological screening Toxicology angiogenesis chick embryo chorioallantoic membrane (CAM) methods retinoic acid toxicological screening tumor growth vascular endothelial grow factor (VEGF) Chorioallantoic Membrane methods angiogenesis tumor growth retinoic acid Animals vascular endothelial grow factor (VEGF) |
| Zdroj: | Journal of applied toxicology : JAT. 42(6) |
| ISSN: | 1099-1263 |
| Popis: | The chorioallantoic membrane (CAM) of the chicken embryo is a highly vascularized extra-embryonic structure that has been widely used as an in vivo model for the evaluation of angiogenesis. This study was designed to optimize data extrapolation from the most exploited experimental protocol to improve its efficiency and the reliability of the obtainable results. In our study, we followed the most common procedure for CAM assay, employing retinoic acid and vascular endothelial growth factor as standards. CAMs were photographed at t |
| Databáze: | OpenAIRE |
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