The neurovascular structure-adjacent frozen-section examination (NeuroSAFE) approach to nerve sparing in robot-assisted laparoscopic radical prostatectomy in a British setting - a prospective observational comparative study
| Autor: | Vinaya Srirangam, Olayinka Gbolahan, Bhavan Prasad Rai, Tim Lane, George Mirmilstein, Ashish Narula, James M. Adshead, Nikhil Vasdev, Samita Agarwal |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Urology medicine.medical_treatment 030232 urology & nephrology 03 medical and health sciences 0302 clinical medicine Robotic Surgical Procedures medicine Potency Frozen Sections Humans Trauma Nervous System Prospective Studies Stage (cooking) Pathological Retrospective Studies Prostatectomy Frozen section procedure business.industry Patient Selection Prostate Prostatic Neoplasms Middle Aged Neurovascular bundle Surgery Treatment Outcome 030220 oncology & carcinogenesis Cohort Laparoscopy Positive Surgical Margin business Organ Sparing Treatments |
| Zdroj: | BJU international. 121(6) |
| ISSN: | 1464-410X |
| Popis: | Objectives To evaluate the NeuroSAFE technique in a British setting in men undergoing RALP. Patients and Methods We retrospectively analysed our prospectively maintained database of patients who underwent RALP between Nov 2008 and Feb 2017. We examined preoperative pathological and functional parameters, intra-operative nerve sparing, post-operative histology as well as functional and oncological follow-up. We compared those who had a NeuroSAFE approach and those who had nerve sparing without NeuroSAFE. We also compared all the RALPs before and after the introduction of NeuroSAFE. Statistical analysis was done using the two tailed T-test and Chi-Squared analysis. Results This single surgeon series included 417 RALPs including 120 NeuroSAFEs. The NeuroSAFE cohort had a greater proportion of D'Amico high risk disease (30.8% vs 9.6%, p |
| Databáze: | OpenAIRE |
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