Comparison of automatic quantification software for the measurement of ventricular volume and ejection fraction in gated myocardial perfusion SPECT
| Autor: | Lum Dp, Coel Mn |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
Male Chest Pain Adolescent Heart Diseases Population Perfusion scanning Coronary Disease Single-photon emission computed tomography Automation Electrocardiography Ventriculography First-Pass Linear regression Medicine Humans Radiology Nuclear Medicine and imaging education Aged Retrospective Studies Aged 80 and over Heart Failure Tomography Emission-Computed Single-Photon education.field_of_study Analysis of Variance Ejection fraction medicine.diagnostic_test business.industry Stroke Volume General Medicine Gold standard (test) Middle Aged Exercise Test End-diastolic volume Female business Nuclear medicine Perfusion Software |
| Zdroj: | Nuclear medicine communications. 24(3) |
| ISSN: | 0143-3636 |
| Popis: | The aim of this study was to compare the performance of three different software packages for the calculation of ejection fraction (EF) and end diastolic volume (EDV) from gated myocardial single photon emission computed tomography studies. Two hundred patients undergoing gated stress myocardial perfusion scans were analysed retrospectively. Patients were grouped as follows: small heart (n=31), normal perfusion scan (n=71), and scan with perfusion defects (n=98). EF and EDV were calculated for each using QGS (Cedars Sinai, Los Angeles, CA), 4D-MSPECT (University of Michigan, Ann Arbor, MI), and ECT (Emory University, Atlanta, GA). Bland-Altman plots, repeated measures ANOVA, and linear regression analysis were used to compare methods. Correlation coefficients between the methods for both EF and EDV were high, greater than 0.9. However, Bland-Altman plots revealed a large standard deviation of the difference between methods, preventing the confident estimate of the value of one method from an observation of another. Despite good correlation, the variance between methods was high. These algorithms behave differently, produce widely variable results from one another, and should not be used interchangeably. It may prove prudent for laboratories to independently validate the software algorithm that is chosen against a 'gold standard' using their own population. |
| Databáze: | OpenAIRE |
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