Dynamics of sperm antibody levels in adolescents with left-sided varicocele
| Autor: | I. V. Rybina, S. V. Pichugova, Ya. B. Beikin |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2020 |
| Předmět: |
varicocele
medicine.medical_specialty 030219 obstetrics & reproductive medicine business.industry urogenital system Immunology Varicocele 030232 urology & nephrology Urology Sperm antibody RC581-607 medicine.disease Left sided sperm antibodies 03 medical and health sciences 0302 clinical medicine varicocelectomy Immunology and Allergy Medicine adolescents Immunologic diseases. Allergy business infertility |
| Zdroj: | Medicinskaâ Immunologiâ, Vol 22, Iss 5, Pp 969-976 (2020) |
| ISSN: | 1563-0625 |
| Popis: | Varicocele means a varicose vein of the spermatic cord, being among the most common disorders diagnosed in childhood and adolescence, which suggests a high risk for infertility. Varicocele is considered an additional factor for immune-dependent infertility which results from damaged hemato-testicular barrier due to venous blood stasis, hyperthermia, testicular ischemia. Our objective was to determine levels of the sperm antibodies in serum and ejaculate in adolescents with left-sided varicocele, in order to assess the changing levels of sperm antibodies in blood serum at different ages during the postoperative period, depending on the degree of varicocele. For adolescents with left-sided varicocele and without varicocele, the serum levels of sperm antibodies were determined annually at the age of 14 to 17 years, as well as registration of sperm antibodies titer in seminal fluid at the age of 17 years. The levels of sperm antibodies in blood serum were traced in dynamics for the main group and comparison group, also comparing the groups with different degrees of varicocele, like as the patients before and after surgical varicocele correction. We did not reveal increased levels of the sperm antibodies over reference values in any subject under study. The level changes of sperm antibodies in serum showed an increase in these indexes at the age of 15-16 years in adolescents of both groups with a trend for a decrease in the comparison group by 17 years of age, however, without such tendency in the main group. No significant differences were found in the levels of sperm antibodies in blood serum depending on the degree of varicocele, and on the time after varicocelectomy. |
| Databáze: | OpenAIRE |
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