Localization of 99mTc-methylene diphosphonate in skin lesions of pseudoxanthoma elasticum
| Autor: | Shantilal Lunia, Danica K. Vedder, Robert B. Chodos |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
Adult
Pathology medicine.medical_specialty integumentary system Apatite crystals business.industry Technetium General Medicine Pseudoxanthoma elasticum medicine.disease Dermatology Affected site medicine.anatomical_structure Dermis medicine Humans Radiology Nuclear Medicine and imaging Female Pseudoxanthoma Elasticum Skin lesion business Radionuclide Imaging 99mTc-Methylene Diphosphonate Skin |
| Zdroj: | Clinical nuclear medicine. 4(5) |
| ISSN: | 0363-9762 |
| Popis: | Increased uptake of 99mTc-methylene diphosphonate (MDP) is demonstrated in a patient with pseudoxanthoma elasticum (PXE) at the affected site. PXE is a hereditary disease with variable expression. Calification of dermal elastic fibers is a characteristic feature of affected skin. Recently, apatite crystals were identified in the affected skin of the patients with PXE. The mechanism of uptake of 99mTc-MDP is probably related to chemisorption of the tracer onto hydroxyapatite crystals in the affected dermis. |
| Databáze: | OpenAIRE |
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