Endocarditis associated with vertebral osteomyelitis and septic arthritis of the axial skeleton
| Autor: | Oscar Murillo, Celina Cabrera, Joan Gómez-Junyent, Imma Grau, Roman Pallares, Alba Ribera, Carmen Peña, Fe Tubau, Javier Ariza |
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| Rok vydání: | 2017 |
| Předmět: |
musculoskeletal diseases
0301 basic medicine Microbiology (medical) Male medicine.medical_specialty Axial skeleton Staphylococcus 030106 microbiology Bacteremia medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Endocarditis Vertebral osteomyelitis Humans 030212 general & internal medicine Aged Retrospective Studies Arthritis Infectious business.industry Osteomyelitis General Medicine Endocarditis Bacterial Middle Aged medicine.disease Streptococcus bovis Infectious Diseases medicine.anatomical_structure Staphylococcus aureus Infective endocarditis Septic arthritis Female Spinal Diseases business Gram-Negative Bacterial Infections Enterococcus |
| Zdroj: | Infection. 46(2) |
| ISSN: | 1439-0973 |
| Popis: | The relationship between infective endocarditis (IE) and osteoarticular infections (OAIs) are not well known. We aimed to study the characteristics of patients with IE and OAIs, and the interactions between these two infections. An observational study (1993–2014) which includes two cohorts: (1) patients with IE (n = 607) and (2) patients with bacteremic OAIs (n = 458; septic arthritis of peripheral and axial skeleton, and vertebral and peripheral osteomyelitis). These two cohorts were prospectively collected, and we retrospectively reviewed the clinical and microbiological variables. There were 70 cases of IE with concomitant OAIs, representing 11.5% of IE cases and 15% of bacteremic OAI cases. Among cases with IE, the associated OAIs mainly involved the axial skeleton (n = 54, 77%): 43 were vertebral osteomyelitis (61%), mainly caused by “less virulent” bacteria (viridans and bovis streptococci, enterococci, and coagulase-negative staphylococci), and 15 were septic arthritis of the axial skeleton (21%), which were mainly caused by Staphylococcus aureus. OAIs with involvement of the axial skeleton were associated with IE (adjusted OR = 2.2; 95% CI 1.1–4.3) independently of age, sex, and microorganisms. Among patients with IE, the associated OAIs mainly involve the axial skeleton. Transesophageal echocardiography should be carefully considered in patients presenting with these bacteremic OAIs. |
| Databáze: | OpenAIRE |
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