Major cell death pathways at a glance
| Autor: | Ellen Wirawan, Linde Duprez, Tom Vanden Berghe, Peter Vandenabeele |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Programmed cell death
Immunology Infections Models Biological Microbiology 03 medical and health sciences AIM2 0302 clinical medicine Animals Humans FADD 030304 developmental biology 0303 health sciences Cell Death biology Autophagy Pyroptosis TRADD Cell biology Multicellular organism Infectious Diseases Apoptosis 030220 oncology & carcinogenesis Host-Pathogen Interactions biology.protein Signal Transduction |
| Zdroj: | Microbes and Infection; Vol 11 |
| ISSN: | 1286-4579 |
| DOI: | 10.1016/j.micinf.2009.08.013 |
| Popis: | Cell death is a crucial process during development, homeostasis and immune regulation of multicellular organisms, and its dysregulation is associated with numerous pathologies. Cell death is often induced upon pathogen infection as part of the defense mechanism, and pathogens have evolved strategies to modulate host cell death. In this review, we will discuss the molecular mechanisms and physiological relevance of four major types of programmed cell death, namely apoptosis, necrosis, autophagic cell death and pyroptosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect