Risk of AIDS related complex and AIDS in homosexual men with persistent HIV antigenaemia
| Autor: | F. De Wolf, Jaap Goudsmit, J. van der Noordaa, J. M. A. Lange, R. A. Coutinho, C. Hooijkaas, Dominik Paul, P. T. A. Schellekens |
|---|---|
| Přispěvatelé: | Other departments |
| Rok vydání: | 1987 |
| Předmět: |
Male
medicine.medical_specialty HIV Antigens Attack rate AIDS-related complex Acquired immunodeficiency syndrome (AIDS) Antigen AIDS-Related Complex Risk Factors Immunopathology Internal medicine Humans Medicine Prospective Studies Antigens Viral General Environmental Science Acquired Immunodeficiency Syndrome biology business.industry General Engineering HIV virus diseases Homosexuality General Medicine medicine.disease Immunology biology.protein General Earth and Planetary Sciences Viral disease Antibody business Research Article |
| Zdroj: | British medical journal (Clinical research ed.), 295(6598), 569-572 |
| ISSN: | 1468-5833 0959-8138 0267-0623 |
| DOI: | 10.1136/bmj.295.6598.569 |
| Popis: | One hundred and ninety eight men seropositive for human immunodeficiency virus (HIV) antibody and 58 HIV antibody seroconverters were studied for an average of 19.3 (SEM 0.5) months to assess the relation between HIV antigenaemia and the risk of developing the acquired immune deficiency syndrome (AIDS) and AIDS related complex. Forty (20.2%) of the 198 HIV antibody seropositive men were antigen positive at entry and remained so during follow up. Eight (13.8%) of the 58 HIV antibody seroconverters and 20 (12.7%) of the remaining 158 HIV antibody seropositive men became antigen positive during follow up, resulting in an end point attack rate for HIV antigenaemia of 14.3%. AIDS related complex was diagnosed in 25 (15.8%) of the HIV antigen negative men and in 14 (20.7%) of the HIV antigen positive men. AIDS was diagnosed in 15 men, resulting in an end point attack rate for AIDS of 23.9% in the HIV antigen positive group and 1.3% in the antigen negative group. HIV antibody seropositive men without symptoms but with persistent HIV antigenaemia are at increased risk of developing AIDS and AIDS related complex. |
| Databáze: | OpenAIRE |
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