Development and evaluation of a passive trunk support system for Duchenne muscular dystrophy patients

Autor: Laura H. C. Peeters, Mohammad Nauzef Mahmood, Micha I. Paalman, Idsart Kingma, Gijsbertus Jacob Verkerke, Jaap H. van Dieën
Přispěvatelé: Extremities Pain and Disability (EXPAND), Personalized Healthcare Technology (PHT), VU University medical center, Neuromechanics, AMS - Restoration and Development
Rok vydání: 2018
Předmět:
Adult
Male
BOYS
030506 rehabilitation
medicine.medical_specialty
Duchenne muscular dystrophy
Posture
Health Informatics
Electromyography
Body weight
lcsh:RC321-571
UPPER-LIMB FUNCTION
Young Adult
03 medical and health sciences
All institutes and research themes of the Radboud University Medical Center
0302 clinical medicine
Physical medicine and rehabilitation
medicine
Humans
Muscle activity
Muscle
Skeletal
lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry
GeneralLiterature_REFERENCE(e.g.
dictionaries
encyclopedias
glossaries)
Braces
medicine.diagnostic_test
business.industry
Research
Rehabilitation
Torso
Equipment Design
ADULTS
JOINTS
Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3]
EFFICACY
medicine.disease
Trunk
Healthy Volunteers
Muscular Dystrophy
Duchenne
Longissimus
LUMBOSACRAL ORTHOSES
MUSCLE-ACTIVITY
Iliocostalis
SURVIVAL
Support system
PROVIDING RESISTIVE FORCE
0305 other medical science
business
030217 neurology & neurosurgery
SPINE
Zdroj: Journal of Neuroengineering and Rehabilitation, 15
Journal of NeuroEngineering and Rehabilitation
Journal of neuroengineering and rehabilitation, 15(1):22. BioMed Central Ltd.
Mahmood, M N, Peeters, L H C, Paalman, M, Verkerke, G J, Kingma, I & van Dieën, J H 2018, ' Development and evaluation of a passive trunk support system for Duchenne muscular dystrophy patients ', Journal of NeuroEngineering and Rehabilitation, vol. 15, no. 1, 22 . https://doi.org/10.1186/s12984-018-0353-3
Journal of NeuroEngineering and Rehabilitation, Vol 15, Iss 1, Pp 1-11 (2018)
Mahmood, M N, Peeters, L H C, Paalman, M, Verkerke, G J, Kingma, I & Van Dieën, J H 2018, ' Development and evaluation of a passive trunk support system for Duchenne muscular dystrophy patients ', Journal of NeuroEngineering and Rehabilitation, vol. 15, no. 1, 22 . https://doi.org/10.1186/s12984-018-0353-3
Journal of Neuroengineering and Rehabilitation, 15(1):22. BMC
Journal of NeuroEngineering and Rehabilitation, 15(1):22. BioMed Central
ISSN: 1743-0003
DOI: 10.1186/s12984-018-0353-3
Popis: BACKGROUND: Patients with Duchenne muscular dystrophy gradually lose the ability to use different muscles of their body. Consequently, they lose the ability to stabilize their trunk against gravity. This hinders them to effectively perform different daily activities. In this paper, we describe the design, realization and evaluation of a trunk orthosis for these patients that should allow them to move their trunk and maintain stability.METHOD: This study aimed to primarily assess the effectiveness of the trunk support system in terms of unloading of trunk muscles, so only healthy participants were recruited for this phase of the study. Measurements were done on 10 healthy participants (23.4±2.07 [M±SD] years old, average body weight 68.42±24.22 [M±SD] kg). The experiment comprised maintaining a constant trunk posture in three different device conditions (control without orthosis and two conditions with different configurations of the orthosis), at four different flexion angles (10°, 20°, 30°, 40°) for each device condition and for two load conditions (with and without stretching the arms). Electromyography (EMG) signals from the trunk muscles were measured to estimate activation levels of the trunk muscles (iliocostalis, longissimus, external oblique and rectus abdominis) and a motion capture system was used to record the movement of the participants during the experiment.RESULTS: Wearing the orthosis caused reductions in longissimus and iliocostalis activity. The average muscle activity level was 5%-10% of maximum voluntary contraction in the unsupported conditions for those particular muscles. This level was reduced to 3%-9% of maximal voluntary contraction for the supported conditions. No effect on external oblique and rectus abdominis activity was observed. Moreover, no pain or discomfort was reported by any of the participants during the experiment. The results from the current experiment also suggests the necessity of lumber stabilizing systems while using trunk orthosis.CONCLUSION: The developed orthosis reduces trunk muscle activation level and provides a solid step for further development of support systems for Duchenne muscular dystrophy patients.TRIAL REGISTRATION: The current study was approved by the medical ethics committee Arnhem-Nijmegen (study number: NL53143.091.15 ), The Netherlands.
Databáze: OpenAIRE
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