Ankylosing spondylitis and systemic sclerosis: a rare combination
Autor: | Nathalie Somogyi-Demerjian, Mireille Nlomé-Nzé, Olivier Meyer, Dieu-Donné Ouédraogo, Elisabeth Palazzo |
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Rok vydání: | 2006 |
Předmět: |
musculoskeletal diseases
Adult Male medicine.medical_specialty Myocarditis Anti-Inflammatory Agents Human leukocyte antigen Scleroderma Rheumatology medicine Humans In patient Spondylitis Ankylosing Esophagus Allele Ankylosing spondylitis Scleroderma Systemic business.industry Histocompatibility Testing Penicillamine medicine.disease Dermatology medicine.anatomical_structure Treatment Outcome HLA-B Antigens Antirheumatic Agents Physical therapy Prednisone Drug Therapy Combination business |
Zdroj: | Joint bone spine. 76(3) |
ISSN: | 1778-7254 |
Popis: | We report a case of diffuse systemic sclerosis (skin, joints, esophagus, and Raynaud's phenomenon) in a 41-year-old Caucasian male with a 15-year history of ankylosing spondylitis and an episode of severe myocarditis of unknown origin. His HLA type included both the B27 allele conferring susceptibility to ankylosing spondylitis and the B35, DRB1 11, and DQB1 03 described as associated with systemic sclerosis. This case-report confirms that two inflammatory joint diseases may co-exist, particularly in patients carrying one or two susceptibility alleles to both diseases. |
Databáze: | OpenAIRE |
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