Upper gastrointestinal bleeding: What has changed during the last 20 years?
| Autor: | M. Schapira, Jean Henrion, Pierre Deltenre, Maisin Jm, J.-M. Ghilain, T. Delaunoit, S. De Maeght, M. Moulart |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Gastrointestinal bleeding medicine.medical_specialty Pediatrics Time Factors Blood transfusion medicine.medical_treatment Gastroenterology Cohort Studies Young Adult Internal medicine Epidemiology medicine Humans Prospective Studies Aged Aged 80 and over medicine.diagnostic_test business.industry General Medicine Middle Aged Prognosis medicine.disease Endoscopy Cohort Etiology Female Upper gastrointestinal bleeding Gastrointestinal Hemorrhage business Esophagitis |
| Zdroj: | Gastroentérologie Clinique et Biologique. 32:839-847 |
| ISSN: | 0399-8320 |
| Popis: | Summary Aim of the study The purpose of this study was to assess the clinical, epidemiological, therapeutic and prognostic changes observed in patients with upper gastrointestinal bleeding (UGIB) during the last two decades. Methods Two cohorts of 200 patients with UGIB consecutively recruited during the period 1984–1987 (cohort A) then during the period 2004-2006 (cohort B) were compared. Results Median age was 61.5 years in the cohort A and 67 years in the cohort B. The main etiologies remained variceal bleeding and peptic ulcer, but esophagitis and Mallory-Weiss syndrome were more frequently observed recently. The intake of gastrotoxic drugs did not decreased despite the widely acknowledged harmful effects of these drugs. Regarding management practices, a therapeutic intervention during the first endoscopy was performed in 36% of the cases in the cohort B but only in 2% of the cases 20 years ago. The frequency and the volume of blood transfusion dramatically decreased during the last two decades. Regarding the outcome, the requirement for surgery and the rate of recurrent bleeding decreased by half, but mortality remained unchanged. Conclusion The main changes observed in patients admitted for UGIB 20 years apart concerned epidemiological features, treatment and prognosis. |
| Databáze: | OpenAIRE |
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