Chronic Epstein-Barr Virus Infection
| Autor: | Timothy Schubert, Scott Biest |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
Adult
Male Herpesvirus 4 Human medicine.medical_specialty Fever of Unknown Origin Asymptomatic Gastroenterology Hepatitis Prednisone Internal medicine medicine Humans Fever of unknown origin Epstein–Barr virus infection Granuloma medicine.diagnostic_test business.industry Liver Diseases Herpesviridae Infections medicine.disease Virology Liver biopsy Chronic Disease Granulomatous Hepatitis medicine.symptom business medicine.drug |
| Zdroj: | Journal of Clinical Gastroenterology. 11:343-346 |
| ISSN: | 0192-0790 |
| DOI: | 10.1097/00004836-198906000-00021 |
| Popis: | A 37-year-old man had fever, weight loss, malaise, right upper quadrant pain, lymphadenopathy, and a twofold elevation of serum alkaline phosphatase, transaminases, and gamma glutamyl transpeptidase. Granulomas were found on liver biopsy after 2 1/2 months of illness. Treatment with isoniazid and rifampin for 2 months did not lead to improvement in fever or symptoms, but prednisone caused a prompt resolution. Positive IgM antibodies to the viral capsule antigen followed by marked elevation of the IgG fraction suggest chronic Epstein-Barr virus infection to be the etiology. The patient was asymptomatic without treatment 14 months after onset of the illness. |
| Databáze: | OpenAIRE |
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