Measurement of coronary bifurcation angle with coronary CT angiography: A phantom study
| Autor: | M. J. Safari, Zhonghua Sun, Chai Hong Yeong, Jeannie Hsiu Ding Wong, Sock Keow Tan, Fadhli Mohamed Sani, Raja Rizal Azman, Kwan Hoong Ng, Sogol Givehchi, Mohammad Nazri Md Shah |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Models Anatomic Computed Tomography Angiography Biophysics General Physics and Astronomy Context (language use) Coronary Artery Disease 030204 cardiovascular system & hematology Coronary Angiography Imaging phantom 030218 nuclear medicine & medical imaging Coronary artery disease 03 medical and health sciences 0302 clinical medicine Imaging Three-Dimensional medicine Humans Radiology Nuclear Medicine and imaging Circumflex Coronary bifurcation Bifurcation Mathematics Observer Variation business.industry Phantoms Imaging Coronary ct angiography Volume rendering General Medicine medicine.disease Coronary Vessels Female Nuclear medicine business |
| Zdroj: | Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). 45 |
| ISSN: | 1724-191X |
| Popis: | Purpose Accurate determination of the bifurcation angle and correlation with plaque buildup may lead to the prediction of coronary artery disease (CAD). This work evaluates two techniques to measure bifurcation angles in 3D space using coronary computed tomography angiography (CCTA). Materials and Methods Nine phantoms were fabricated with different bifurcation angles ranging from 55.3° to 134.5°. General X-ray and CCTA were employed to acquire 2D and 3D images of the bifurcation phantoms, respectively. Multiplanar reformation (MPR) and volume rendering technique (VRT) were used to measure the bifurcation angle between the left anterior descending (LAD) and left circumflex arteries (LCx). The measured angles were compared with the true values to determine the accuracy of each measurement technique. Inter-observer variability was evaluated. The two techniques were further applied on 50 clinical CCTA cases to verify its clinical value. Results In the phantom setting, the mean absolute differences calculated between the true and measured angles by MPR and VRT were 2.4° ± 2.2° and 3.8° ± 2.9°, respectively. Strong correlation was found between the true and measured bifurcation angles. Furthermore, no significant differences were found between the bifurcation angles measured using either technique. In clinical settings, large difference of 12.0° ± 10.6° was found between the two techniques. Conclusion In the phantom setting, both techniques demonstrated a significant correlation to the true bifurcation angle. Despite the lack of agreement of the two techniques in the clinical context, our findings in phantoms suggest that MPR should be preferred to VRT for the measurement of coronary bifurcation angle by CCTA. |
| Databáze: | OpenAIRE |
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