Rheostat Coordination of Latent Kaposi Sarcoma-Associated Herpesvirus RNA Expression in Single Cells
Autor: | JJ L. Miranda, Nicole C. Rondeau |
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Rok vydání: | 2021 |
Předmět: |
herpesviruses
latent infection Lymphoma viruses Immunology Genomics Biology medicine.disease_cause Microbiology Kaposi’s sarcoma-associated herpesvirus Virology Kaposi sarcoma-associated herpesvirus genomics medicine Humans Latency (engineering) Kaposi's sarcoma-associated herpesvirus Antigens Viral Sarcoma Kaposi Letter to the Editor Gene Interleukin-6 Nuclear Proteins virus diseases RNA Promoter biochemical phenomena metabolism and nutrition Virus Latency Rna expression Insect Science Herpesvirus 8 Human |
Zdroj: | Journal of Virology |
ISSN: | 1098-5514 0022-538X |
Popis: | We detected precise coordination of RNA levels between two latent genes of the Kaposi sarcoma-associated herpesvirus (KSHV) using single-cell RNA sequencing. LANA and vIL6 are expressed during latency by different promoters on remote regions of the episome.…. |
Databáze: | OpenAIRE |
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