Acute monoblastic leukemia (FAB-M5b) with t(8;14)(p11;q11.1)
| Autor: | Jerree A. Stroh, Marilyn L. Slovak, S. Thomas Traweek, Lakshmi J. Nemana |
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| Rok vydání: | 1991 |
| Předmět: |
Aged
80 and over Chromosomes Human Pair 14 Male Cancer Research Breakpoint Chromosomal translocation Biology medicine.disease medicine.disease_cause Virology Translocation Genetic Immunophenotyping Acute Monoblastic Leukemia Antigen Karyotyping Leukemia Monocytic Acute Genetics medicine Humans Acute monocytic leukemia Carcinogenesis Molecular Biology Aged Chromosomes Human Pair 8 |
| Zdroj: | Cancer genetics and cytogenetics. 56(2) |
| ISSN: | 0165-4608 |
| Popis: | A case of acute monocytic leukemia (FAB-M5b) expressing natural killer cell-associated antigens containing a t(8;14)(p11;q11.1) is presented. We interpret this translocation to represent a variant of the t(8;16) previously reported in FAB-M5b. These findings support the contention that the 8p11 breakpoint site is the critical junction in the oncogenesis of acute monoblastic leukemia with differentiation. |
| Databáze: | OpenAIRE |
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