Kaposi sarcoma in association with molluscum contagiosum: an uncommon diagnosis in a single biopsy and potential diagnostic pitfall
| Autor: | Satya Vara Prasad Busarla, Rosalynn M. Nazarian, Devon C. Gimbel, Aliyah R. Sohani, Shahin Sayed, Zahir Moloo |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Molluscum Contagiosum Cutaneous kaposi sarcoma Biopsy Dermatology Pathology and Forensic Medicine Bleomycin Immunocompromised Host Biomarkers Tumor Medicine Neoplasm Humans Sampling (medicine) Diagnostic Errors Antigens Viral Sarcoma Kaposi Molluscum contagiosum Antibiotics Antineoplastic medicine.diagnostic_test AIDS-Related Opportunistic Infections business.industry Coinfection Remission Induction Nuclear Proteins General Medicine medicine.disease Treatment Outcome Skin biopsy Herpesvirus 8 Human Sarcoma business |
| Zdroj: | The American Journal of dermatopathology. 34(1) |
| ISSN: | 1533-0311 |
| Popis: | Molluscum contagiosum is a cutaneous poxviral infection that is rarely associated with other skin diseases, such as cutaneous neoplasms. Such associations are likely to be coincidental, except in immunocompromised patients. Kaposi sarcoma, an angioproliferative neoplasm derived from lymphatic endothelium, is mediated by human herpes virus-8 infection and occurs with increased frequency in immunocompromised individuals. We report an unusual case of molluscum contagiosum with underlying cutaneous Kaposi sarcoma diagnosed in a single skin biopsy of a human immunodeficiency virus-positive patient. Our case highlights the importance of adequate sampling to avoid missing secondary diagnoses in histopathologic sections and alerts pathologists and dermatologists to the possibility of coinfection in high-risk patients by 2 virally-mediated skin conditions. |
| Databáze: | OpenAIRE |
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