Change in antiepileptic drug prescription patterns for pregnant women with epilepsy over the years: Impact on pregnancy and fetal outcomes

Autor:	Ramandeep Bansal, Praveen Kumar, Parampreet S Kharbanda, Pooja Sikka, Vanita Suri, Seema Chopra, Subhas Chandra Saha, Neelam Aggarwal
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Adult medicine.medical_specialty Antiepileptic drugs Antiepileptic drug 030226 pharmacology & pharmacy Group B 03 medical and health sciences Epilepsy Young Adult 0302 clinical medicine Fetus Obstetrics and gynaecology Pregnancy medicine Birth Weight Humans Pharmacology (medical) 030212 general & internal medicine Medical prescription Practice Patterns Physicians' Pharmacology Obstetrics business.industry Cesarean Section Infant Newborn fetal and maternal outcomes Abnormalities Drug-Induced Stillbirth medicine.disease women with epilepsy Infant Small for Gestational Age Anticonvulsants Female Levetiracetam business medicine.drug Research Article
Zdroj:	Indian Journal of Pharmacology
ISSN:	1998-3751 0253-7613
Popis:	AIMS AND OBJECTIVES: The objectives of the study were: (1) to determine if there is a change in pattern of antiepileptic drug (AED) prescription during pregnancy in women with epilepsy (WWE) attending a tertiary care institute in North India and (2) to determine if change in AED prescription pattern has resulted in improved fetal and maternal outcomes in WWE. PATIENTS AND METHODS: The current study was a retrospective analysis of records of WWE attending a medical and surgical disorder clinic of obstetrics and gynecology department of a tertiary care teaching hospital in North India. We retrospectively collected data of all the patients during the 5-year period from 2011 to 2015 (Group A) (n = 177) and compared it with our previously published data during the years 1987–1994 (Group B) (n = 219). RESULTS: There was significantly higher use of (i) levetiracetam (LEV) in Group A compared to Group B when women on monotherapy were compared (P
Databáze:	OpenAIRE
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