A Case of Cardiac Dysfunction Associated with Monoclonal Gammopathy of Undetermined Significance
| Autor: | Il Suk Sohn, Sung-Jig Lim, Jin-Man Cho, Suk-Tae Jang, Chong-Jin Kim, Eun-Sun Jin |
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| Rok vydání: | 2009 |
| Předmět: |
Male
Pathology medicine.medical_specialty Paraproteinemias Cardiomyopathy Diastole Case Report Immunoelectrophoresis Immunoglobulin kappa-Chains Bone Marrow Biopsy Ventricular Dysfunction medicine Humans Ultrasonography medicine.diagnostic_test business.industry Amyloidosis General Medicine Middle Aged medicine.disease medicine.anatomical_structure Echocardiography Monoclonal Bone marrow Cardiomyopathies business Monoclonal gammopathy of undetermined significance |
| Zdroj: | Journal of Korean Medical Science |
| ISSN: | 1011-8934 |
| Popis: | The monoclonal gammopathies (MG) are monoclonal neoplasms related to each other by virtue of their development from common progenitors in the B lymphocyte lineage. Cardiac dysfunction in patients with MG is not well established. We experienced a case of cardiac dysfunction associated with MG identified by echocardiography and biopsy. Fifty nine year-old man was admitted because of dyspnea for several months. Echocardiography revealed diastolic dysfunction showing restrictive physiology with elevated left ventricular filling pressure. Bone marrow (BM) studies and immunoelectrophoresis were compatible with monoclonal gammopathy of undetermined significance. Endomyocardial, BM, and enteral biopsies for ruling out for amyloidosis (Congo-red stain) were negative. This is the case of non-amyloidotic light chain deposition cardiomyopathy. |
| Databáze: | OpenAIRE |
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