Impact of Epidemic Influenza A–Like Acute Respiratory Illness in a Remote Jungle Highland Population in Irian Jaya, Indonesia
| Autor: | Maidy Pranata Putri, N. Cox, C. Hayes, N. Sukri, Ria P Larasati, G. Ingkokusumo, E. Burni, H. Z. Muslim, B. Subianto, C. H. Simanjuntak, Andrew L. Corwin, Kanti Laras |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Rural Population Microbiology (medical) Adolescent Attack rate Population medicine.disease_cause Influenza Human Case fatality rate Influenza A virus Humans Medicine Child education Retrospective Studies education.field_of_study Respiratory tract infections business.industry Infant Respiratory infection Outbreak Middle Aged Virology Infectious Diseases Indonesia Case-Control Studies Child Preschool Population study business Demography |
| Zdroj: | Clinical Infectious Diseases. 26:880-888 |
| ISSN: | 1537-6591 1058-4838 |
| DOI: | 10.1086/513917 |
| Popis: | A suspected epidemic of unknown etiology was investigated in April/May 1996 in the remote jungle highlands of easternmost Indonesia. Trend analysis demonstrates the area-wide occurrence of a major respiratory infection outbreak in November 1995 through February 1996. The monthly mean rate of respiratory infection episodes for the peak outbreak months (2,477 episodes/100,000 persons) was significantly higher (P < .0001) than for the 34 months leading up to the outbreak (109 episodes/100,000 persons). Notable were the high attack rates, particularly among adults: 202 episodes/1,000 persons aged 20-50 years in one community. Excess morbidity attributed to the outbreak was an estimated 4,338 episodes. The overall case-fatality rate was 15.1% of outbreak cases. Laboratory evidence confirmed the circulation of influenza A/Taiwan/1/86-like viruses in the study population, and high hemagglutination inhibition titer responses were indicative of recent infections. Historical documents from neighboring Papua New Guinea highlight the role of influenza A virus in repeated area outbreaks. |
| Databáze: | OpenAIRE |
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