Alveolar hemorrhage associated with cocaine consumption
| Autor: | Leticia Casimiro-Guzmán, Lourdes N Vélez-Ramírez, Jaime D Mondragón, Lorena Rebeca Arce-Negrete, Jesús Alberto López-García, Omar Jiménez-Zarazúa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Pulmonary and Respiratory Medicine
Adult Lung Diseases Male Orthopnea medicine.medical_specialty Hemoptysis Hemorrhage 030204 cardiovascular system & hematology Critical Care and Intensive Care Medicine law.invention Sepsis 03 medical and health sciences Cocaine-Related Disorders 0302 clinical medicine Fatal Outcome Cocaine law medicine Humans Intensive care medicine Lung Cause of death business.industry Diffuse alveolar hemorrhage Emergency department medicine.disease Intensive care unit medicine.anatomical_structure 030228 respiratory system medicine.symptom Cardiology and Cardiovascular Medicine Vasculitis business |
| Zdroj: | HEART & LUNG, 47(5), 525-530. MOSBY-ELSEVIER |
| ISSN: | 0147-9563 |
| DOI: | 10.1016/j.hrtlng.2018.05.022 |
| Popis: | Cocaine is an illegal drug; its abuse and toxicity are a public health problem due to its high morbidity and mortality. Cocaine can affect the cardiovascular, central nervous and respiratory systems. The case of a 42-year-old male without history of chronic or degenerative diseases, but previous cocaine consumption is presented in this report. The patient is admitted to the Emergency Department given that the clinical presentation included hemoptysis and dyspnea with mild to minimal activity, which evolved to orthopnea. Advanced airway management was required and supportive care at the Intensive Care Unit was provided. Imaging studies showed evidence compatible with alveolar hemorrhage diagnosis. In search of an autoimmune etiology, an antibody-screening panel was requested, reporting negative results for autoimmune disorders. The patient management was based on corticosteroid therapy and plasmapheresis to counter the persistent hemoptysis and hemoglobin serum level decline. The management strategy was based on the clinical suspicion of vasculitis and a torpid clinical evolution. Pulmonary sepsis ensued, resulting in patient's death. The necropsy report describes the primary cause of death as diffuse alveolar hemorrhage secondary to diffuse alveolar injury. This case report presents the detailed clinical, imagining and histopathological findings of a patient with alveolar hemorrhage secondary to cocaine consumption, as well as a review of the literature. |
| Databáze: | OpenAIRE |
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