High-Resolution Esophageal Manometry in Myasthenia Gravis
| Autor: | Gustavo Torres-Barrera, Héctor J. Maldonado-Garza, Sami R. Achem, Susana Isabel Scharrer, Daniel Eduardo Benavides-Salgado, Gilberto Herrera-Quiñones |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Weakness Case Report Edrophonium Gastroenterology Neuromuscular junction 03 medical and health sciences 0302 clinical medicine Esophagus Internal medicine otorhinolaryngologic diseases medicine Acetylcholine receptor Autoimmune disease business.industry Muscle weakness General Medicine medicine.disease Dysphagia Myasthenia gravis medicine.anatomical_structure 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology medicine.symptom business medicine.drug |
| Zdroj: | ACG Case Reports Journal |
| ISSN: | 2326-3253 |
| Popis: | Myasthenia gravis (MG) is an autoimmune disease that affects the postsynaptic membrane at the neuromuscular junction. In MG, antibodies bind to acetylcholine receptors inducing muscle weakness. The weakness typically increases with exercise and repetitive muscle use. Improvement of muscular weakness after rest and/or administration of anticholinesterase drugs (edrophonium) are characteristic of MG. We report a patient with unexplained dysphagia, dysphonia, and dysarthria, whose diagnosis was suggested by high-resolution esophageal motility and edrophonium infusion. We highlight the importance of dysphagia as presenting or dominant symptom in MG and review the esophageal motility findings in this rare, but treatable disorder. |
| Databáze: | OpenAIRE |
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