Can intracranial time-of-flight-MR angiography predict extracranial carotid artery stenosis?
| Autor: | Filiz Osmanodja, Ramanan Ganeshan, Jochen B. Fiebach, Kersten Villringer, Jan F. Scheitz |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Male
medicine.medical_specialty Constriction Pathologic Magnetic resonance angiography medicine.artery medicine Humans Carotid Stenosis ddc:610 Stroke Ischemic Stroke Retrospective Studies Neuroradiology medicine.diagnostic_test business.industry Intracranial Embolism Ultrasound Area under the curve medicine.disease Stenosis Neurology Ischemic Attack Transient Female Neurology (clinical) Radiology Internal carotid artery business Carotid Artery Internal Magnetic Resonance Angiography |
| Popis: | Objectives Extracranial stenosis of the internal carotid artery (ICA) is an important cause of ischemic stroke and transient ischemic attack (TIA). It can be diagnosed using contrast-enhanced CT or MR angiography (MRA) as well as Doppler ultrasound. In this study, we assessed the diagnostic value of intracranial time-of-flight (TOF) MRA to predict extracranial ICA stenosis (ICAS). Methods We retrospectively analyzed consecutive patients with acute ischemic stroke or TIA and middle- (50–69%) or high-grade (70–99%) unilateral extracranial ICAS according to NASCET criteria assessed by ultrasound between January 2016 and August 2018. The control group consisted of patients without extracranial ICAS. Intraluminal signal intensities (SI) of the intracranial ICA on the side of the extracranial stenosis were compared to the contralesional side on TOF-MRA source images. SI ratios (SIR) of contralesional:lesional side were compared between groups. Results In total, 151 patients were included in the main analysis. Contralesional:lesional SIR in the intracranial C4-segment was significantly higher in patients with ipsilateral extracranial ICA stenosis (n = 51, median 74 years, 57% male) compared to the control group (n = 100, median 68 years, 48% male). Mean SIR was 1.463 vs. 1.035 (p p Conclusions SIR on TOF-MRA can be a marker of extracranial ICAS. |
| Databáze: | OpenAIRE |
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