Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínico
| Autor: | David Güenchor García, Baldo Espinoza Cohen, José Valenzuela Cruz, Franklin Ablan Candia, Michel Galleguillos Valdivia, Antonio Zapata Pizarro, Víctor García Jara |
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| Rok vydání: | 2020 |
| Předmět: |
Adrenocortical Hyperfunction
medicine.diagnostic_test business.industry medicine.medical_treatment Tumor Embolism Adrenalectomy Adrenal Gland Neoplasms Soft tissue Magnetic resonance imaging General Medicine medicine.disease Nephrectomy Abdominal Neoplasms medicine Carcinoma Amenorrhea medicine.symptom business Nuclear medicine Cushing Syndrome hirsutism |
| Zdroj: | Revista médica de Chile v.148 n.11 2020 SciELO Chile CONICYT Chile instacron:CONICYT |
| ISSN: | 0034-9887 |
| Popis: | We report a previously healthy 34-year-old woman, presenting with a seven-month history of arterial hypertension, amenorrhea, weight gain, facial edema, acne, hirsutism and low back pain. A CT scan showed a right adrenal mass of 18 × 13 × 12.5 cm, and multiple vertebral and rib fractures. The hormonal study confirmed Cushing's Syndrome. Ketoconazole, spironolactone, cotrimoxazole, calcium / vitamin D were started. An adrenalectomy with a right nephrectomy were performed. The excised tumor measured 16 cm and weighed 1.55 kg. There was tumor embolism and a 4 mm soft tissue involvement (pT3NxMx). The right kidney was free of tumor. The patient was treated with chemotherapy (etoposide plus cisplatin). Study of vertebral fractures with magnetic resonance (MRI) showed crush fractures, without images of metastatic bone lesions. One year after surgery, a CT scan showed no signs of tumor recurrence. The patient was lost from follow-up thereafter. |
| Databáze: | OpenAIRE |
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