The perception of touch and the ventral somatosensory pathway

Autor: Felix Blankenburg, Sabrina D. Thiel, Jon Driver, Arno Villringer, Bogdan Draganski, Anna Kosatschek, Sven Preusser, Burkhard Pleger, Elisabeth Roggenhofer, Carolin Rook
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Adult
Male
Adolescent
Insular cortex
Somatosensory system
Functional Laterality
Statistics
Nonparametric
Perceptual Disorders
White matter
Young Adult
Neural Pathways
Image Processing
Computer-Assisted
medicine
Humans
Aged
Neurologic Examination
Brain Mapping
Postcentral gyrus
Secondary somatosensory cortex
Putamen
Somatosensory Cortex
Middle Aged
Magnetic Resonance Imaging
medicine.anatomical_structure
nervous system
Touch
Somatosensory evoked potential
Brain Injuries/complications
Brain Injuries/pathology
Female
Functional Laterality/physiology
Neural Pathways/pathology
Perceptual Disorders/etiology
Perceptual Disorders/pathology
Somatosensory Cortex/pathology
Touch/physiology
Brain Injuries
Touch Perception
Neurology (clinical)
Psychology
Neuroscience
psychological phenomena and processes
Reports
Zdroj: Brain
Brain : A Journal of Neurology, vol. 138, no. Pt 3, pp. 540-548
Popis: In humans, touching the skin is known to activate, among others, the contralateral primary somatosensory cortex on the postcentral gyrus together with the bilateral parietal operculum (i.e. the anatomical site of the secondary somatosensory cortex). But which brain regions beyond the postcentral gyrus specifically contribute to the perception of touch remains speculative. In this study we collected structural magnetic resonance imaging scans and neurological examination reports of patients with brain injuries or stroke in the left or right hemisphere, but not in the postcentral gyrus as the entry site of cortical somatosensory processing. Using voxel-based lesion-symptom mapping, we compared patients with impaired touch perception (i.e. hypoaesthesia) to patients without such touch impairments. Patients with hypoaesthesia as compared to control patients differed in one single brain cluster comprising the contralateral parietal operculum together with the anterior and posterior insular cortex, the putamen, as well as subcortical white matter connections reaching ventrally towards prefrontal structures. This finding confirms previous speculations on the 'ventral pathway of somatosensory perception' and causally links these brain structures to the perception of touch.
Databáze: OpenAIRE
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