Terpenoids in four Inula species from Bulgaria

Autor: Plamena Staleva, Victoria Ivanova, Antoaneta Trendafilova, Ina Aneva, Milka Todorova
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of the Serbian Chemical Society, Vol 86, Iss 12, Pp 1229-1240 (2021)
ISSN: 1820-7421
0352-5139
Popis: Phytochemical study of the chloroform extract of the aerial parts of Inula germanica L., I. ensifolia L., I. conyza (Griess.) DC. and I. salicina L. led to the identification of 33 terpenoids. ?- and ?-amyrin, lupeol, taraxasterol, ?-taraxasterol and their 3-O-acetates and 3-O-palmitates were identified by GC/MS. In addition, the structures of 3-O-palmitates of mainaladiol, arnidiol, faradiol and 16-hydroxylupeol were confirmed by NMR. ent-Kaur-16-en-19- -oic acid and its 15?-(3-methylpentanoyloxy) and 15?-(3-methylbutanoyloxy) derivatives were isolated from I. conyza. Ten closely related sesquiterpene lactones (germacranolides and melampolides) were found in I. germanica and their structural identification was performed by spectral analyses. I. ensifolia and I. salicina were free of sesquiterpene lactones and diterpenoids. All triterpenoids and diterpenoids, grazielia acid, desacetylovatifolin and 8-(2-methylbutanoyloxy)- 1(10),4,11(13)-germacrutrien-6,12-olide-14-oic acid are described for the first time in the studied species. The principal component analysis was used to find a relationship between th? investigated up to now Inula species, growing in Bulgaria.
Databáze: OpenAIRE