The Oral Fluid MEMS/NEMS Chip (OFMNC): Diagnostic & Translational Applications
| Autor: | Paul C. Denny, David T.W. Wong, Chih-Ming Ho, Lawrence E. Wolinsky, Benjamin M. Wu, Fengxia Qi, Yang Li, Wenyuan Shi, Carlo D. Montemagno |
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| Rok vydání: | 2005 |
| Předmět: |
Proteomics
0301 basic medicine Disease status medicine.medical_specialty Disease onset Computer science Treatment outcome Biosensing Techniques Disease Bioinformatics 03 medical and health sciences 0302 clinical medicine Microchip Analytical Procedures medicine Humans Nanotechnology Medical physics Salivary Proteins and Peptides Oral Diagnosis Saliva Nanoelectromechanical systems Disease surveillance Diagnosis Oral 030206 dentistry General Medicine 030104 developmental biology Protein Biosynthesis RNA Oral fluid Biomarkers |
| Zdroj: | Advances in Dental Research. 18:3-5 |
| ISSN: | 1544-0737 0895-9374 |
| Popis: | The ability to monitor health status, disease onset and progression, and treatment outcome through non-invasive means is a most desirable goal in health-care promotion and delivery. There are three prerequisites for this goal to be realized: specific biomarkers associated with a health or disease state, a non-invasive approach to detect and monitor the biomarkers, and the technologies to discriminate between and among the biomarkers. We present a roadmap to achieve these goals using oral fluids as the diagnostic medium to scrutinize the health and/or disease status of individuals. This is an ideal opportunity to bridge state-of-the-art micro-/nano-electromechanical system (MEMS/NEMS) sensors to oral fluid for diagnostic applications. As the "mirror of body", oral fluid is a perfect medium to be explored for health and disease surveillance. The translational applications and opportunities are enormous. |
| Databáze: | OpenAIRE |
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