Localization of aquaporins in the mouse vestibular end organs

Autor:	Matti Anniko, Masaya Takumida, Akinobu Kakigi, Hiroshi Takumida, Rie Nishioka, Naoya Egami
Rok vydání:	2013
Předmět:	Pathology medicine.medical_specialty Sensory Receptor Cells Scarpa's ganglion Sensory system Biology Aquaporins Endolymphatic sac Mice Ganglia Sensory otorhinolaryngologic diseases medicine Animals Inner ear Vestibular system Epithelial Cells General Medicine Fluid transport Immunohistochemistry medicine.anatomical_structure Otorhinolaryngology Mice Inbred CBA sense organs Endolymphatic Sac Transduction (physiology)
Zdroj:	Acta Oto-Laryngologica. 133:804-813
ISSN:	1651-2251 0001-6489
Popis:	Conclusion: We found that aquaporins (AQPs) in the fluid transporting cells, such as vestibular dark cells and endolymphatic sac epithelial cells, seem to be of importance in fluid transport in the inner ear, while those in the sensory and ganglion cells may play a functional role in sensory cell transduction. Objective: Expression of AQPs (0–12) was analyzed in normal mouse vestibular end organs. Methods: CBA/J mice were used in this study. Localization of AQPs 0–12 in the vestibular end organs and endolymphatic sac was investigated by immunohistochemistry. Results: The AQPs were found abundantly distributed in many structures in the vestibular end organs, i.e. vestibular sensory and supporting cells, vestibular dark cells, vestibular ganglion cells, and the endolymphatic sac.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7abaace780e3523144bc074b89e440 https://doi.org/10.3109/00016489.2013.783717 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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