Lenalidomide stops progression of multifocal epithelioid hemangioendothelioma including intracranial disease
Autor: | Anne Berthold, Ashley Sumrall, Ruth Fredericks, Grace Shumaker |
---|---|
Rok vydání: | 2009 |
Předmět: |
Adult
Cancer Research medicine.medical_specialty Pathology Neurology medicine.medical_treatment Antineoplastic Agents Disease Hemangioendothelioma Liver disease medicine Humans Epithelioid hemangioendothelioma Lenalidomide Chemotherapy Clinical Trials as Topic business.industry Brain Neoplasms medicine.disease Magnetic Resonance Imaging Thalidomide Radiation therapy Oncology Hemangioendothelioma Epithelioid Female Neurology (clinical) business Tomography X-Ray Computed medicine.drug |
Zdroj: | Journal of neuro-oncology. 97(2) |
ISSN: | 1573-7373 |
Popis: | Epithelioid Hemangioendothelioma (EH) is a rare soft-tissue tumor which may present as an isolated tumor or can spread to affect internal organs. The course of EH varies, based on the tissue of origin. This case report describes a young woman who developed cutaneous EH with concurrent intracranial disease during pregnancy. After resection, the lesions returned. Even after several courses of chemotherapy and radiotherapy, the patient developed multifocal disease including pulmonary, skeletal, and liver disease. She now exhibits stable disease after approximately 6 years of therapy with lenalidomide. |
Databáze: | OpenAIRE |
Externí odkaz: |