Neuropathic Pain: From Mechanism to Clinical Application
| Autor: | Emily A. Ramirez, Lauren E. Ta, Charles L. Loprinzi, Anthony J. Windebank |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
0303 health sciences
medicine.medical_specialty education.field_of_study business.industry Population Chronic pain Disease medicine.disease Dermatology 3. Good health Lesion 03 medical and health sciences 0302 clinical medicine Peripheral neuropathy Epidemiology Neuropathic pain medicine Etiology medicine.symptom education business 030217 neurology & neurosurgery 030304 developmental biology |
| Zdroj: | Peripheral Neuropathy-A New Insight into the Mechanism, Evaluation and Management of a Complex Disorder |
| DOI: | 10.5772/55277 |
| Popis: | A lesion or disease affecting the somatosensory system can cause a wide range of pathophy‐ siologic symptoms including mild or severe chronic pain. Due to the diversity of etiologies giving rise to nervous system damage that generates neuropathic pain, it has become a ubiquitous health concern without respect for geographic or socioeconomic boundaries [1]. Within the developing world, infectious diseases [2-4] and trauma [5] are the most common sources of neuropathic pain syndromes. The developed world, in contrast, suffers more frequently from diabetic polyneuropathy (DPN) [6, 7], post herpetic neuralgia (PHN) from herpes zoster infections [8], and chemotherapy-induced peripheral neuropathy (CIPN) [9, 10]. There is relatively little epidemiological data regarding the prevalence of neuropathic pain within the general population, but a few estimates suggest it is around 7-8% [11, 12]. Despite the widespread occurrence of neuropathic pain, treatment options are limited and often ineffective, leaving many to live with the persistent agony and psychosocial burden associated with chronic pain [13, 14]. |
| Databáze: | OpenAIRE |
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