Lipofuscin and the principles of fundus autofluorescence: a review
| Autor: | Namrata Nandakumar, Sheldon M. Buzney, John J. Weiter |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
genetic structures Light Fundus Oculi Retinal Pigment Epithelium Lipofuscin Macular Degeneration Optical imaging Ophthalmology Geographic Atrophy Medicine Animals Humans Fluorescein Angiography Retinal pigment epithelium medicine.diagnostic_test business.industry Optical Imaging General Medicine Macular degeneration medicine.disease Fluorescein angiography eye diseases Fundus autofluorescence Geographic atrophy Oxidative Stress medicine.anatomical_structure lipids (amino acids peptides and proteins) sense organs business |
| Zdroj: | Seminars in ophthalmology. 27(5-6) |
| ISSN: | 1744-5205 |
| Popis: | Fundus autofluorescence is a non-invasive imaging modality that measures lipofuscin that has accumulated in the retinal pigment epithelium (RPE). Excessive lipofuscin in the RPE is a common pathway found in several diseases including Stargardt’s disease and age-related macular degeneration. This review discusses the role of photooxidative damage in the development of lipofuscin and the principles of fundus autofluorescence. |
| Databáze: | OpenAIRE |
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