Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser

Autor: Cláudia Helena Silva-Lovato, Viviane de Cássia Oliveira, Vanessa Maria Fagundes Leite, Maurício Malheiros Badaró, Carolina Noronha Ferraz de Arruda, Raphael Freitas de Souza, Marcela Moreira Salles, Helena de Freitas Oliveira Paranhos, Cássio do Nascimento
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Male
Time Factors
Sodium Hypochlorite
Surface Properties
DESINFECÇÃO COM HIPOCLORITO DE SÓDIO
medicine.medical_treatment
Colony Count
Microbial
Dentistry
law.invention
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Patient satisfaction
Randomized controlled trial
Double-Blind Method
Cleanser
law
Candidiasis
Oral
medicine
Humans
030212 general & internal medicine
Denture Cleansers
General Dentistry
Saline
Aged
Analysis of Variance
business.industry
Ricinus
Biofilm
Denture
Complete
Upper
Candidiasis
Reproducibility of Results
030206 dentistry
Original Articles
Antimicrobial
Denture
lcsh:RK1-715
Disinfection
Logistic Models
Treatment Outcome
chemistry
Patient Satisfaction
Sodium hypochlorite
lcsh:Dentistry
Biofilms
Anti-Infective Agents
Local
Female
Dentures
business
Zdroj: Journal of Applied Oral Science v.25 n.3 2017
Journal of applied oral science
Universidade de São Paulo (USP)
instacron:USP
Journal of Applied Oral Science, Vol 25, Iss 3, Pp 324-334
Journal of Applied Oral Science, Volume: 25, Issue: 3, Pages: 324-334, Published: JUN 2017
Journal of Applied Oral Science
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Popis: The development of opportunistic infections due to poor denture hygiene conditions justified the search for effective hygiene protocols for controlling denture biofilm. Objective This study evaluated Ricinus communis and sodium hypochlorite solutions in terms of biofilm removal ability, remission of candidiasis, antimicrobial activity, and participant satisfaction. Material and Methods It was conducted a controlled clinical trial, randomized, double-blind, and crossover. Sixty-four denture wearers with (n=24) and without candidiasis (n=40) were instructed to brush (3 times/day) and immerse their dentures (20 min/day) in different storage solutions (S1 / S2: 0.25% / 0.5% sodium hypochlorite; S3: 10% R. communis; S4: Saline).The trial period for each solution was seven days and a washout period of seven days was used before starting the use of another solution. The variables were analyzed at baseline and after each trial period. The biofilm of inner surfaces of maxillary dentures was disclosed, photographed, and total and dyed areas were measured (Image Tool software). The percentage of biofilm was calculated. Remission of candidiasis was assessed by visual scale and score were attributed. Antimicrobial activity was assessed by the DNA-Checkerboard hybridization method. Patient satisfaction was measured using a questionnaire. Results S1 (4.41±7.98%) and S2 (2.93±5.23%) were more effective then S3 (6.95±10.93%) in biofilm remotion(P
Databáze: OpenAIRE
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