Confirmation of trace level residues in the food supply
| Autor: | Emil G. Siegmund, Thomas Cairns |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Chemistry
Detection threshold Sample (material) General Medicine Mass spectrometric Drug Residues Mass Spectrometry Industrial and Manufacturing Engineering Trace Elements Trace (semiology) Identification (information) Risk analysis (engineering) Analytical problem Environmental chemistry Food supply Reference standards Food Analysis Food Science |
| Zdroj: | Critical Reviews in Food Science and Nutrition. 30:397-402 |
| ISSN: | 1549-7852 1040-8398 |
| DOI: | 10.1080/10408399109527550 |
| Popis: | With the recent proliferation of mass spectrometric methods available for the identification and confirmation of various compounds in different environmental matrices, it is timely to address the criteria desirable in a regulatory sample case. The emphasis of this review is on the experimental process of confirmation at concentration levels in the range of low parts per million (ppm) to parts per trillion (ppt). At such levels, various data manipulations or alternate choices of approaching the analytical problem of confirmation must be employed to ensure an acceptable result. The problems experienced when dealing with nanogram levels in analysis are much more complex than when recording a mass spectrum of an ample supply of a reference standard. This review reflects an interpretation of the developing status of confirmation since there does not yet exist “accepted criteria”. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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