The use of preserved tissue in finite element modelling of fresh ovine vertebral behaviour
| Autor: | Ruth K. Wilcox, Philippa E. Garner, Sarrawat Rehman, Jean E. Aaron |
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| Rok vydání: | 2013 |
| Předmět: |
Materials science
Finite Element Analysis Biomedical Engineering Bioengineering Thoracic Vertebrae Bone volume fraction Fresh Tissue medicine Animals Body Weights and Measures Vertebral bone Embalming Sheep Reproducibility of Results Stiffness Organ Size General Medicine Anatomy Elasticity Finite element method Computer Science Applications Vertebra Human-Computer Interaction medicine.anatomical_structure Tissue Preservation Tomography medicine.symptom Fe model Tomography X-Ray Computed |
| Zdroj: | Computer Methods in Biomechanics and Biomedical Engineering. 16:1163-1169 |
| ISSN: | 1476-8259 1025-5842 |
| DOI: | 10.1080/10255842.2012.654782 |
| Popis: | The aim of this study was to investigate whether the predicted finite element (FE) stiffness of vertebral bone is altered when using images of preserved rather than fresh tissue to generate specimen-specific FE models. Fresh ovine vertebrae were used to represent embalmed (n = 3) and macerated dry-bone (n = 3) specimens and treated accordingly. Specimens were scanned pre- and post-treatment using micro-computed tomography. A constant threshold level derived from these images was used to calculate the respective bone volume fraction (BV/TV) from which the conversion factor validated for fresh tissue was used to determine material properties that were assigned to corresponding FE models. Results showed a definite change in the BV/TV between the fresh and the preserved bone. However, the changes in the predicted FE stiffness were not generally greater than the variations expected from assignment of loading and boundary conditions. In conclusion, images of preserved tissue can be used to generate FE models that are representative of fresh tissue with a tolerable level of error. |
| Databáze: | OpenAIRE |
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