Innate immune responses of young bulls to a novel environment
| Autor: | Elisabetta Razzuoli, Pietro Calà, Fabrizio Lazzara, Massimo Amadori, Leonardo Nanni Costa, Emilio Olzi, Simona Cafazzo, Angelo Ferrari, L. Archetti, Diego Magnani, Andrea Vitali, Nicola Lacetera |
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| Přispěvatelé: | Razzuoli, Elisabetta, Olzi, Emilio, Calà, Pietro, Cafazzo, Simona, Magnani, Diego, Vitali, Andrea, Lacetera, Nicola, Archetti, Laura, Lazzara, Fabrizio, Ferrari, Angelo, NANNI COSTA, Leonardo, Amadori, Massimo |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
0301 basic medicine medicine.medical_specialty Stre Climate Immunology Serum albumin Alpha (ethology) Acute phase proteins Acute phase protein Transportation Hemolytic Complement medicine.disease_cause Stress 03 medical and health sciences Animal science Internal medicine medicine Animals Psychological stress Animal Husbandry Cytokine Young bulls Cytokines Innate immunity Veterinary (all) Innate immune system General Veterinary biology Temperature 0402 animal and dairy science Acute-phase protein Albumin 04 agricultural and veterinary sciences Animal husbandry 040201 dairy & animal science Immunity Innate 030104 developmental biology Endocrinology biology.protein Cattle Young bull |
| Popis: | Animal welfare during transportation has been investigated in several studies, as opposed to post-transportation phases. In this study, we evaluated the effect of a novel environment after transportation on 26 Friesian bulls, 242 ± 42 day-old, from ten different dairy farms. Animals were shipped to a breeding center in different seasons, and selected parameters of innate immunity (serum bactericidal activity, hemolytic complement, serum albumin, α, β, and γ-globulins, interleukin-6, TNF-α) were monitored before and after the arrival at days--4/0/4/15/30. Our results showed significant differences of IL-6 and TNF-α protein levels at destination in December (94 ± 1.3 pg/ml) and June (+788 pg/ml), respectively. Moreover, the serum levels of these cytokines increased between days 0 and 15 after the arrival, the modulation of IL-6 being in agreement with established models of physical and/or psychological stress. Concerning the modulation of albumin, alpha and beta-globulins, the highest levels were detected in April, whereas a significant decrease was observed between day 15 and 30 after arrival; on the contrary, γ-globulin levels significantly increased after day 15. The results of this study highlight the occurrence of innate immune responses of young bulls to the combined effects of climate (season) and novel farming conditions. |
| Databáze: | OpenAIRE |
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