Current applications of plasmapheresis in clinical toxicology
| Autor: | Dimitar S. Nenov, Petko Marinov, Vesselin D. Nenov, Julia Sabeva |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Male
Paraquat medicine.medical_treatment Amitriptyline Mushroom Poisoning Pharmacology Toxicology Risk Assessment Sensitivity and Specificity medicine Humans Theophylline Amanita phalloides Diltiazem Antidote Transplantation biology business.industry Poisoning Plasmapheresis biology.organism_classification Hemoperfusion Survival Rate Treatment Outcome Nephrology Anesthesia Verapamil Female business medicine.drug |
| Zdroj: | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 18 |
| ISSN: | 0931-0509 |
| Popis: | The clinical applications of plasmapheresis are rapidly increasing in number and scope. This trend is also observed in the application of plasmapheresis as a method of detoxification in clinical toxicology. Because of a lack of large controlled series, the rationale for using plasmapheresis must be confirmed in each type of intoxication by evidence of effective clearance, as well as by high plasma protein binding and a low volume of distribution of the toxic substance. Plasmapheresis is used mostly to treat phalloid mushroom intoxications. In this potentially fatal intoxication, for which there is no antidote, plasmapheresis is at least as effective as haemoperfusion in reducing mortality from as high as 30–50% with conventional therapy to |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|