Association of PAHs and BTEX exposure with lung function and respiratory symptoms among a nonoccupational population near the coal chemical industry in Northern China
| Autor: | Yanyan Dai, Guocheng Hu, Zhencheng Xu, Ruifang Fan, Laiguo Chen, Yanshan Lv |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Male China Population Maximal Midexpiratory Flow Rate Urine BTEX 010501 environmental sciences 01 natural sciences Pulmonary function testing 03 medical and health sciences chemistry.chemical_compound Young Adult Forced Expiratory Volume Benzene Derivatives Medicine Humans Respiratory system Polycyclic Aromatic Hydrocarbons Benzene education Child Lung function lcsh:Environmental sciences 0105 earth and related environmental sciences General Environmental Science Aged Pollutant lcsh:GE1-350 education.field_of_study Air Pollutants business.industry Environmental Exposure Middle Aged Coal Industry 030104 developmental biology chemistry Environmental chemistry Chemical Industry Female business Biomarkers |
| Zdroj: | Environment International, Vol 120, Iss, Pp 480-488 (2018) |
| ISSN: | 0160-4120 |
| Popis: | Emissions (particularly aromatic compounds) from coal industries and biomass fuels combustion lead to high health risks for neighboring residents. To investigate the association of polycyclic aromatic hydrocarbons (PAHs) and benzene, toluene, ethylbenzene and 1,2-dimethylbenzene (BTEX) exposure with lung function and respiratory symptoms among adults and children near the coal-chemical industry in Northern China, adults and children from a county dotted with coal chemical industry were chosen as subjects for investigation (investigated area, IR). The control group consisted of adults and children from an agricultural county (control area, CR). The environmental and urinary PAH and BTEX levels of adults and children were determined by isotope dilution liquid chromatography coupled with tandem mass spectrometry. The Mann-Whitney U test and multivariate linear regression models were used to analyze the relationship between pollutant exposure and the respiratory system. The results showed that in an ambient environment, levels of PAHs and BTEX in the IR were significantly higher than those in the CR. Particularly, the concentration profiles for air samples were IR > CR and indoor > outdoor. Both for adults and children, the geometric (GM) concentrations of urinary PAHs and BTEX from the IR were significantly higher than those measured in the CR. Additionally, the urinary PAH exposure level profiles of smokers were higher than those of nonsmokers, indicating that indoor air and smoking were both important nonoccupational exposure sources. The decline of the forced expiratory in the first second (FEV1, %) and the forced expiratory middle flow rate (FEF25%) in children were associated with increasing urinary PAH metabolite levels (p |
| Databáze: | OpenAIRE |
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