An epidemiological study of dengue in Delhi, India

Autor: B N Nagpal, Aparup Das, Anushrita, Rekha Saxena, Olivier Telle, Neena Valecha, Richard Paul, Himmat Singh, Veena Pande, N R Tuli, Kumar Vikram, N K Yadav, Aruna Srivastava, Sanjeev Kumar Gupta, Anup Anvikar
Přispěvatelé: National Institute of Malaria Research [New Dehli, Inde] (NIMR), Indian Council of Medical Research [New Dehli] (ICMR), Department of Biotechnology, Kumaon University, Municipal Corporation of Delhi, Génétique fonctionnelle des Maladies infectieuses - Functional Genetics of Infectious Diseases, Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur [Paris], Authors are thankful to Paster Institut, Paris, France for the funding support ANR. We are also thankful to MCD for helping us in selection of study sites in Delhi. We thank the entire field staff for their careful performance in serological testing and data collection., Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS)
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Male
Pediatrics
MESH: Dengue/epidemiology
Dengue virus
medicine.disease_cause
Dengue fever
Dengue
0302 clinical medicine
MESH: Aged
80 and over

MESH: Child
Epidemiology
Mass Screening
030212 general & internal medicine
MESH: Incidence
Child
Aged
80 and over

education.field_of_study
Rapid diagnostic test
[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases
MESH: Middle Aged
MESH: Epidemiologic Studies
Incidence
Incidence (epidemiology)
Asymptomatic infection
Middle Aged
3. Good health
MESH: India/epidemiology
Infectious Diseases
Child
Preschool

Female
medicine.symptom
Adult
medicine.medical_specialty
Adolescent
Veterinary (miscellaneous)
030231 tropical medicine
Population
MESH: Mass Screening/statistics & numerical data
India
Asymptomatic
Young Adult
03 medical and health sciences
medicine
Humans
education
Mass screening
Aged
MESH: Adolescent
MESH: Humans
business.industry
Secondary dengue infection
MESH: Child
Preschool

Infant
Primary dengue infection
MESH: Adult
Dengue Virus
medicine.disease
Epidemiologic Studies
Index case
MESH: Dengue Virus/isolation & purification
Insect Science
Immunology
Parasitology
business
MESH: Female
Zdroj: Acta Tropica
Acta Tropica, Elsevier, 2016, 153, pp.21-27. ⟨10.1016/j.actatropica.2015.09.025⟩
Acta Tropica, 2016, 153, pp.21-27. ⟨10.1016/j.actatropica.2015.09.025⟩
ISSN: 0001-706X
DOI: 10.1016/j.actatropica.2015.09.025⟩
Popis: International audience; Delhi, the capital of India, is an important metropolitan hub for major financial and sociocultural exchanges, offering challenging threats to current public health infrastructure. In recent past, an upsurge of dengue cases in Delhi posed a significant menace to the existing dengue control policies. To reform the control strategies and take timely intervention to prevent future epidemics, an epidemiological study on the proportion of both asymptomatic and symptomatic dengue infections in selected population was conducted. The aim of the study was to investigate and assess the epidemiology of dengue infection and to estimate the proportion of asymptomatic and symptomatic dengue infections in Delhi. In this study, around 50 confirmed dengue cases, a total of 2125 individuals as household and neighbourhood contacts, with or without dengue febrile illness, were finger pricked and serologically detected as dengue positive or negative using SD Duo Bioline Rapid Diagnostic Test (SD Inc, Korea) with NS1, IgM & IgG combo test, which detected dengue virus antigen and antibodies to dengue virus in human blood. Out of 2125 individuals , 768 (36.1%) individuals showed positive dengue test with past (25.5%), primary (1.88%) or secondary (8.8%) dengue infections. Higher percentage of IgG was found in age groups 15–24 years and 25–50 years (36% each). Infants (
Databáze: OpenAIRE