Burkitt's lymphoma patients in Northwest Cameroon have a lower incidence of sickle cell trait (Hb AS) than healthy controls
| Autor: | D T Jam, Richard Bardin, Martin Kidd, P B Hesseling, D D Palmer, G S Tuh, P Wharin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Reduced risk medicine.medical_specialty Sickle cell trait business.industry General Medicine medicine.disease Gastroenterology Lymphoma Lower incidence 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis Internal medicine Immunology Medicine Haemoglobin electrophoresis business Burkitt's lymphoma |
| Zdroj: | SAMJ: South African Medical Journal, Volume: 106, Issue: 7, Pages: 686-686, Published: 2016 |
| Popis: | Contradictory findings have been reported from Africa with regard to the risk of developing Burkitt’s lymphoma (BL) in sickle cell trait (AS) carriers. Haemoglobin electrophoresis was performed in 78 BL patients in the Northwest region of Cameroon, and in 78 nearest-neighbour controls of the same age, sex and tribe from the same village. AS was confirmed in 4 of 78 (5.13%) BL patients and in 11 of 78 (14.10%) controls (χ2, p=0.052; Fisher’s exact, one-tailed, p=0.050). Sickle cell trait carriers had a marginal statistically reduced risk of developing BL. |
| Databáze: | OpenAIRE |
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