Superinfection during treatment of nosocomial infections with tigecycline
| Autor: | Manuel E. Jiménez-Mejías, M. V. Gil Navarro, M. J. Gómez-Gómez, Jerónimo Pachón, Hospitale Universitarios Virgen del Rocío, Carlos Ortiz-Leyba, Emilio García-Cabrera, Elisa Cordero |
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| Rok vydání: | 2009 |
| Předmět: |
Microbiology (medical)
Adult Male medicine.medical_specialty medicine.drug_class viruses Antibiotics Minocycline Tigecycline Biology medicine.disease_cause Microbiology Medical microbiology Pharmacotherapy Internal medicine parasitic diseases medicine Prevalence Humans Antibacterial agent Aged Retrospective Studies Cross Infection Bacteria Pseudomonas aeruginosa virus diseases General Medicine Bacterial Infections biochemical phenomena metabolism and nutrition Middle Aged Anti-Bacterial Agents Infectious Diseases Superinfection Etiology Female medicine.drug |
| Zdroj: | European journal of clinical microbiologyinfectious diseases : official publication of the European Society of Clinical Microbiology. 29(7) |
| ISSN: | 1435-4373 |
| Popis: | We performed a retrospective and observational study of 51 patients treated with tigecycline, as the treatment for nosocomial infections due to multidrug-resistant microorganisms, to evaluate the superinfection rate and their etiologies. Superinfections were diagnosed in 12 (23.5%) patients (seven due to Pseudomonas aeruginosa, 13.7%) and one patient had P. aeruginosa colonization. Five patients with superinfection died (41.6%), three due to superinfections and two to underlying diseases. The superinfection rate observed during tigecycline treatment is higher than that previously reported. Pseudomonas aeruginosa is the most frequent agent, being the cause of 58.5% of all superinfections. |
| Databáze: | OpenAIRE |
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